NaturAr
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General Characteristics
NatID
346
Common Name
4R*, 5S*, 6S*, 7R*, 8S*, 9S*)-4α,5β-epoxy-8b-(2-methylbutanoyloxy)-9α-acetoxy-10-carbomethoxy-melampo-1(10),11(13)-dien-6α,12-olide
Molecular Formula
C23H30O9
Chemical Class
Prenol lipids > Terpene lactones
Molecular Weight
450.189 g/mol
Other names
Representations
Smiles
C=C1C(=O)O[C@H]2[C@H]1[C@H](OC(=O)[C@@H](C)CC)[C@@H](OC(C)=O)C(C(=O)OC)=CCC[C@@]1(C)O[C@H]21
Inchi
InChI=1S/C23H30O9/c1-7-11(2)20(25)30-17-15-12(3)21(26)31-18(15)19-23(5,32-19)10-8-9-14(22(27)28-6)16(17)29-13(4)24/h9,11,15-19H,3,7-8,10H2,1-2,4-6H3/t11-,15+,16-,17-,18-,19+,23+/m0/s1
Inchi Key
GKJXWJCWUAEWDP-KCGLZOHMSA-N
3D Structure
Download
Calculated Properties
clogP
2.02
TPSA
117.73
HBD
0
HBA
9
Rotatable Bonds
5
Aromatic Rings
0
Heavy Atoms
32
Aromatic Carbocycles
0
Aromatic Heterocycles
0
Number of NO
9
Experiments
EID
Source
Semisynthetic?
Confidence level
References
9958
Smallanthus connatus
No
High
Bach, S. M., Schuff, C., Grau, A., & Catalán, C. A. N. (2007). Melampolides and other constituents from Smallanthus connatus. Biochemical Systematics and Ecology, 35(11), 785–789. https://doi.org/10.1016/j.bse.2007.03.015
Bioassays
Bioassay ID
NPASS ID
Target
Activity type
Activity